Genomics

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In their book just out, Genomics: A Revolution in Health and Disease Discovery, husband and wife team of Whitney Stewart and Hans C. Andersson, MD, tackle genetic health issues and breakthroughs. They begin with early history of genetics and continue with discoveries up to the present day, giving an accurately researched scientific standpoint in understandable and readable lay terms. 

Laced into this science, they have the personal case studies of real people who are affected by genetically borne physical diseases and conditions. They show how DNA has been important to a range of professions including zoologists, archeologists, and forensic scientists. Particularly in medicine, the ability to diagnose problems at birth or sometimes in utero can change lives if treatment starts early before a disease has made inroads into the baby’s physical and mental health. A cautionary tale about relying on consumer DNA sites in chapter six by itself makes the book worth reading. Ethical and social issues are addressed such as insurance companies that withhold coverage for some issues based on genetic information and how family planning will be addressed when one is known to be a carrier for a disability. 

Looking forward, since this work is not finished, they list a website for those who would like to participate in some of the studies. In the epilogue, they point to the possibility of precision medicine in a new field known as pharmacogenetics as doctors and pharmacists consider a person’s genetics combined with diet, lifestyle, and environment and to the importance of doctors and humanitarian experts working together to guide the future of genetics in society. Back matter includes a helpful glossary and resources. 

The book is listed as teens and young adults, but any person who has or cares about those with an inherited autoimmune disease or health problem will not want to miss this easily understood and current treatment of the topic. I found it a fascinating afternoon read but well worth a return revisit for some of the information.